PMH58 TOOL: MULTI-ATTRIBUTE UTILITY FUNCTION REFLECTING PATIENT EXPERIENCE OF SIDE EFFECTS TO ANTIPSYCHOTIC THERAPY
نویسندگان
چکیده
منابع مشابه
Pharmacogenetics of antipsychotic-induced side effects
Currently available antipsychotic drugs (APDs) carry significant though highly variable, liability to neurologic and metabolic side effects. Pharmacogenetics approaches offer the possibility of identifying patient-specific biomarkers for predicting risk of these side effects. To date, a few single nucleotide polymorphisms (SNPs) in a handful of genes have received convergent support across mult...
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There are two central issues to consider in assessing the motor side effects of atypical antipsychotic (AA) drugs. The fi rst is the defi nition of what it means to be an AA drug. While one review states that ‘the defi ning characteristic of an AA is its lower risk of inducing EPS [extra pyramidal symptoms] [1]’ there is, in fact, no consensus defi nition [2] of what it means to be ‘atypical’. ...
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We consider multi-attribute Bayesian optimization, where each design in an optimization problem’s feasible space is associated with a vector of attributes that can be evaluated via a time-consuming computer code, and each vector of attributes is assigned a utility according to a decision-maker’s utility function. A standard Bayesian optimization approach could be applied if the utility function...
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Background & Objective: Drug abuse causes severe gastrointestinal, neurological problems and dependency. For maintenance therapy of opiate addiction, long-acting opioids like methadone are used. Since incorrect use of methadone, leads to serious complications, this study aimed to evaluate the prevalence of methadone. Materials & Methods: This cross-sectional study was done with a sample size of...
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BACKGROUND Capturing service users' perspectives can highlight additional and different concerns to those of clinicians, but there are no up to date, self-report psychometrically sound measures of side effects of antipsychotic medications. Aim To develop a psychometrically sound measure to identify antipsychotic side effects important to service users, the Maudsley Side Effects (MSE) measure. ...
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ژورنال
عنوان ژورنال: Value in Health
سال: 2009
ISSN: 1098-3015
DOI: 10.1016/s1098-3015(10)74777-x